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Therapeutic target identified to neutralise toxic forms of Parkinson's-associated protein - EurekAlert


<p>Researchers from the Universitat Aut&ograve;noma de Barcelona (UAB) have identified a region in the early aggregates of the alpha-synuclein protein that can be targeted to prevent its conversion into the toxic amyloid fibrils that accumulate in the brains of people suffering from Parkinson&#39;s disease. The discovery was recently published in the <em>Journal of the American Chemical Society</em>, in a study that advances the comprehension of the structural properties of these initial aggregates, or oligomers, and opens the door to developing new therapeutic strategies for their inactivation.</p>

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