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Therapeutic target identified to neutralise toxic forms of Parkinson's-associated protein - EurekAlert
<p>Researchers from the Universitat Autònoma de Barcelona (UAB) have identified a region in the early aggregates of the alpha-synuclein protein that can be targeted to prevent its conversion into the toxic amyloid fibrils that accumulate in the brains of people suffering from Parkinson's disease. The discovery was recently published in the <em>Journal of the American Chemical Society</em>, in a study that advances the comprehension of the structural properties of these initial aggregates, or oligomers, and opens the door to developing new therapeutic strategies for their inactivation.</p>
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