Get the latest Science News and Discoveries
Researchers identify a key metabolic gene as target for improved cancer immunotherapy - EurekAlert
Researchers at the VIB-KU Leuven Center for Cancer Biology have identified a potential target for cancer immunotherapy. The team, led by Professor Massimiliano Mazzone found that the CDA gene is among the top upregulated metabolic genes in immunotherapy-resistant tumors. Inhibiting this gene through pharmacologic or genetic intervention led to better T-cell infiltration, increasing effectiveness of immunotherapy in a type of pancreatic cancer called PDAC. The results of the study have been published in Nature Cancer.
None
Or read this on Eureka Alert