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Guest molecules ride perfect waves in dna droplets—A breakthrough for synthetic biology

Scientists have uncovered a previously unknown type of molecular motion inside DNA-based droplets: instead of spreading randomly, guest molecules advance in an organized wave. This surprising discovery opens the door to understanding how cells might organize internal processes without membranes. Using customizable DNA condensates as experimental models, the team showed how molecular waves emerge through precise DNA interactions. These insights could not only transform our grasp of cellular signaling but may even lay groundwork for treating neurodegenerative diseases by influencing how molecules behave inside aging cells.

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