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Cooperative proteins help the immune system identify and attack invaders - EurekAlert
Salk scientists discovered how macrophages, which act as the immune system's first line of defense, tailor their specific responses to various intruders through the independent and cooperative functions of three SWI/SNF protein complex variants: cBAF, ncBAF, and PBAF. The findings provide new insight into macrophage-initiated inflammation, which can potentially be utilized to create therapeutics that modulate excessive and damaging inflammation during disease.
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