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Changes Upstream: RIPE team uses CRISPR/Cas9 to alter photosynthesis for the first time - EurekAlert
A RIPE team used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, this study, published in Science Advances, is the first unbiased gene-editing approach to increase gene expression and downstream photosynthetic activity. The approach is more difficult than transgenic breeding, but could potentially preempt regulatory issues by changing DNA already within the plant, allowing the plants to get in the hands of farmers sooner.
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