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Stanford Medicine study identifies a CXCL10–IFN-γ–driven immune pathway explaining rare cases of myocarditis after mRNA COVID-19 vaccination, shows why the risk is highest in young males, and confirms that COVID-19 infection itself is about ten times more likely to cause myocarditis.

A new study implicates a pair of substances secreted by immune cells in inducing myocarditis among mRNA-based COVID-19 vaccine recipients — and proposes a strategy to mitigate this effect.

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