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Why aortic aneurysms form at the arch or in the abdominal segment - EurekAlert
A vascular dilatation in the aorta can be life-threatening if it bursts. These so-called aortic aneurysms typically form in the same sites of the large blood vessel: either on the upper arch or in the abdominal cavity. “We wanted to understand why it is always these sites that are affected. What is it that sets them apart from others?” points out Professor Daniela Wenzel, Head of the Department of Systems Physiology at Ruhr University Bochum, Germany. Research into the gene activity of the innermost vascular layer showed that even in healthy mice abnormalities occur at precisely these sites. The research team published their findings in the journal Angiogenesis on July, 5, 2024.
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