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USC researchers pioneer new brain imaging technique through clear “window” in patient's skull - EurekAlert


In the first study of its kind, researchers from the Keck School of Medicine of USC and the California Institute of Technology (Caltech) designed and implanted a transparent window in the skull of a patient, then used functional ultrasound imaging (fUSI) to collect high-resolution brain imaging data through the window. Their preliminary findings suggest that this sensitive, non-invasive approach could open new avenues for patient monitoring and clinical research, as well as broader studies of how the brain functions. The research participant sustained a traumatic brain injury from a skateboarding accident. Before the reconstructive surgery, the research team tested and optimized fUSI parameters for brain imaging, using both a phantom (a scientific device designed to test medical imaging equipment) and animal models. They then collected fUSI data from while the patient completed  several tasks, both before surgery and after the clear implant was installed, finding that the window offered an effective way to measure brain activity.

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