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The World Health Organization reporting system for lung cytopathology–a review of the first edition - EurekAlert
Lung cancer remains the leading cause of cancer-related mortality and is the second most frequently diagnosed cancer globally in both men and women. Early and accurate diagnosis through lung cytopathology, which examines specimens such as sputum, bronchial brushings (BB), bronchial washings (BW), bronchoalveolar lavage (BAL), and fine needle aspiration biopsy (FNAB), is critical for effective treatment. The advent of endobronchial ultrasound (EBUS) has significantly enhanced the diagnostic utility of FNAB by allowing simultaneous diagnosis and staging. Given the increasing importance of precise lung tumor classification for molecular testing, there is a pressing need for standardized terminology and reporting standards in lung cytopathology. The World Health Organization (WHO) has developed a new reporting system aimed at achieving this standardization to improve communication between cytopathologists and clinicians, enhance diagnostic accuracy, and facilitate research and clinical trial participation.
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