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The molecular basis of how Pradimicin A binds to viral N-glycan, a potential SARS-CoV-2 entry inhibitor - EurekAlert
HIV, Ebola and most recently, COVID-19 viruses have had an enormous impact on our societies world-wide. All these viruses are ‘enveloped viruses,’ viruses that have an exterior envelope that surrounds them largely composed of its host’s cells. This envelope increases the virus’s ability to hide from their host’s immune system and to access the host’s cells. It also, however, gives researchers a target, an opportunity to interrupt viral transmission.
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