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Targeting the undruggables ---- the power of protein degraders - EurekAlert
Targeted protein degradation technology is a breakthrough drug development strategy for challenging drug targets. This new form of drug development includes various types such as PROTAC, molecular glue, LYTAC, ATTEC, AUTAC, AUTOTAC, DAC, etc. This review systematically summarizes the application of targeted protein degradation technology in the development of degraders for challenging drug targets.
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