Get the latest Science News and Discoveries

Splicing it all together in the fight against cancer - EurekAlert


Osaka University researchers developed molecules, called splice-switching oligonucleotides (SSOs) that bind to the RNA molecules encoding a protein known as REST. In neuroendocrine tumors, these RNAs are incorrectly spliced together, which supports the cancerous phenotype. When injected into tumors in laboratory mice, SSOs could help restore normal REST function, leading to reduced tumor size. This novel approach is a promising new tool for treating neuroendocrine tumors that do not respond to conventional therapies.

None

Get the Android app

Or read this on Eureka Alert

Read more on:

Photo of EurekAlert

EurekAlert

Photo of Cancer

Cancer

Photo of fight

fight

Related news:

News photo

Serendipity reveals new method to fight cancer with T cells

News photo

Public fails to appreciate risk of consuming raw milk, survey finds - EurekAlert

News photo

A Global Heat Early Warning system is now essential, and requires planning in four key areas to overcome barriers and ... - EurekAlert