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Skeletal stem cells in bone development, homeostasis, and disease - EurekAlert


This review discusses the role of skeletal stem cells (SSCs) in bone development, homeostasis, and disease. Recent advancements have identified that SSCs are not a uniform population; rather, they vary across different skeletal sites and developmental stages. Techniques such as fluorescence-activated cell sorting, lineage tracing, and single-cell sequencing have been instrumental in mapping SSCs' lineage trajectories and understanding their characteristics in various physiological and pathological contexts.

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