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Researchers advocate for structured framework to study the benefits of exercise training in multiple sclerosis ... - EurekAlert


Sandroff and colleagues review current literature on exercise training in MS and outline an experimental medicine framework as a pathway to accelerate progress at a field-wide level for better integrating exercise training into MS rehabilitation protocols. This framework comprises four main steps: identifying CNS targets for intervention, selecting outcomes that reflect the CNS targets, developing interventions that modulate those targets, and conducting robust clinical trials to precisely determine the extent to which changes in the CNS targets are the reason for exercise-related improvements in clinical outcomes.

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