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New study links protein secreted by blood vessels to drug-resistant cancer - EurekAlert
<p><strong>Cancer stem cells (CSCs) are a small subset of adaptive malignant cells that promote tumor growth and drug resistance. Recently, researchers from Japan reported that Sfrp1, an angiocrine factor secreted by tumor blood vessels, plays a key role in the maintenance of CSC populations. Their findings clarify the elusive role of this factor, which could pave the way to novel treatments targeting vascular endothelial cells that nurture CSCs in drug-resistant cancers.</strong></p>
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