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Mount Sinai study identifies genetic link bet - EurekAlert

Researchers at the Icahn School of Medicine at Mount Sinai have made a significant discovery, identifying genetic connections between inflammatory bowel disease (IBD) and Parkinson’s disease (PD). Published in Genome Medicine on May 13, their study highlights the potential for joint therapeutic strategies to target these two challenging disorders. The team, led by Meltem Ece Kars, MD, PhD, a postdoctoral researcher at The Charles Bronfman Institute for Personalized Medicine; Yuval Itan, PhD, Associate Professor of Genetics and Genomic Sciences; and Inga Peter, PhD, Professor of Genetics and Genomic Sciences at Icahn Mount Sinai, used advanced genomic analysis techniques to investigate the genetic overlap between IBD and PD. Their findings point to mutations in the LRRK2 gene as a common element linking both conditions and identify novel genes that are likely to be affected in people experiencing both IBD and PD.

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