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Microscopic heist: How lung bacteria forge weapons to steal iron and survive

Researchers investigating the enigmatic and antibiotic-resistant Pandoraea bacteria have uncovered a surprising twist: these pathogens don't just pose risks they also produce powerful natural compounds. By studying a newly discovered gene cluster called pan, scientists identified two novel molecules Pandorabactin A and B that allow the bacteria to steal iron from their environment, giving them a survival edge in iron-poor places like the human body. These molecules also sabotage rival bacteria by starving them of iron, potentially reshaping microbial communities in diseases like cystic fibrosis.

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