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In this 1799 letter, Thomas Jefferson said "despotism had overwhelmed the world for thousands & thousands of years" but "science can never be retrograde; what is once acquired of real knowledge can never be lost."

This is from my letter to William G. Munford, June 18, 1799: I am among those who think well of the human character generally. I consider man as formed for society, and endowed by nature with those dispositions which fit him for society. I believe also that his mind is perfectible to a degree of w

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