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Identification of key of transposable elements associated with myocarditis based on RNA and single-cell sequencing ... - EurekAlert
This study explores the role of transposable elements (TEs) in modulating immune responses in cardiomyopathy, using RNA-Seq and single-cell sequencing data from a mouse model of experimental autoimmune myocarditis. Findings reveal significant upregulation of immune genes and specific expression of ERVB7-1.LTR-MM transposon across various immune cells, suggesting TEs' substantial impact on the disease's immune mechanisms.
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