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How a protein component of nuclear pore complexes regulates development of blood cells and may contribute to ... - EurekAlert
Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA processes that influence cell survival, proliferation, and differentiation. Research suggests NPCs in cancer cells are different and in the latest study, scientists at Sanford Burnham Prebys identify a key protein in NPCsd that contributes to the development of myeloid cells, blood cells that if not formed or working properly leads to myeloid disorders such as leukemias.
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