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Genetics of gallstone disease and their clinical significance - EurekAlert
Gallstone disease is a common condition, affecting approximately 10-20% of the global adult population. Of these, about 20% develop symptomatic disease, leading to significant healthcare utilization. The formation of gallstones is a multifactorial process, influenced by both genetic and environmental factors. Advances in genetic analysis have identified specific genetic variants that contribute to the development of gallstone disease, providing new insights into its pathogenesis and potential avenues for personalized treatment.
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