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Exploration of polymer cononsolvency mechanism through soft X-ray absorption spectroscopy - EurekAlert


This study investigates the cononsolvency mechanism of poly(N-isopropylacrylamide) (PNIPAM), which is soluble in pure methanol (MeOH) and water but insoluble in aqueous MeOH solutions. Combining oxygen K-edge X-ray absorption spectroscopy (XAS) with theoretical calculations executed in molecular dynamics (MD) simulations and inner-shell calculations, it was found that hydrophobic interactions between PNIPAM and MeOH clusters play a key role in PNIPAM aggregation and cononsolvency emergence.

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