urea

Urea, also known as carbamide, is an organic compound with chemical formula CO₂. This amide has two –NH₂ groups joined by a carbonyl functional group. Urea serves an important role in the metabolism of nitrogen-containing compounds by animals and is the main nitrogen-containing substance in the urine of mammals. It is a colorless, odorless solid, highly soluble in water, and practically non-toxic. Dissolved in water, it is neither acidic nor alkaline. The body uses it in many processes, most notably nitrogen excretion. The liver forms it by combining two ammonia molecules with a carbon dioxide molecule in the urea cycle. Urea is widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. Friedrich Wöhler discovered that urea can be produced from inorganic starting materials, which was an important conceptual milestone in chemistry in 1828.

Read more in the app

Scientists Unveil Urea’s Secret Role in the Origin of Life

How urea may have been the gateway to life

Scientists discover urea in atmosphere revealing profound consequences for climate

Astrocytic urea cycle in the brain controls memory impairment in Alzheimer's disease

Urea-powered microrobots bust up bacterial films

A new single-atom catalyst can produce hydrogen from urea at an exceptional rate

Pretreating nuisance green algae with lye, urea increases bacterial production of biogas

Novel matrix-based slow-release urea improves crop production

Novel diarylamides as orally active diuretics targeting urea transporters

Novel catalysts improve efficiency of urea synthesis at ambient conditions

50 years ago, urea showed promise as a sickle-cell treatment