Sanaria
Sanaria is a biotechnology company developing vaccines protective against malaria and now recently COVID-19, as well as related products for use in malaria research. Sanaria's vaccines are based on the use of the sporozoite stage of the malaria Plasmodium parasite as immunogen. The SPZ stage of the malaria parasite is inoculated into humans by mosquito bite. Sanaria has developed the technology to grow and harvest aseptic, purified Plasmodium falciparum SPZ and formulate them for use in vaccines for human use. Pf is responsible for the most of the approximately 500,000 deaths caused by malaria annually. Sanaria's most advanced candidate vaccine is called Sanaria® PfSPZ Vaccine, which uses radiation attenuated SPZ, that cannot divide or cause disease, to induce these protective immune responses.