Mutations

In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication (translesion synthesis).

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Our thirst for pineapple may be causing mutations in Costa Rica’s sloths

Mutations in hereditary Alzheimer's disease damage neurons without 'usual suspect' amyloid plaques

Mutations in same gene allow two different groups of humans to thrive at extreme altitudes

Laboratory experiments and genomic work in B. subtilis hints that just a few mutations in key genes are enough to help colonizing bacteria spread.

DNA's 'topography' influences where cancer-causing mutations appear

Bird flu viruses have mutations that might help them spread to humans

Older trees accumulate more mutations than their younger counterparts

Language Impairments Unraveled: How Mutations in a Language Gene Produce Speech Deficits

“Silent” Mutations Make Noise In Cancer

Scientists discover how mutations in a language gene produce speech deficits

Vaccine developers can't keep up with COVID's mutations

How a rural school teacher became a top COVID sleuth: A self-taught Indiana man is among a cadre of community scientists who scour the SARS-CoV-2 genome for problematic mutations.

Fewer Unwanted Mutations – New Technique Opens the Door to Safer Gene Editing

Maternally Inherited Diseases: New Technology Uncovers Hidden Mitochondrial DNA Mutations

Comprehensive atlas of gene mutations in human tissue

Cockroach Sex Took a Strange Turn. Now More Mutations Have Emerged.

Cancer Breakthrough: “Hard To Lose” Mutations in Tumors May Predict Response to Immunotherapy

Artificial Intelligence Takes On Cancer: AI Analysis of Mutations Could Lead to Improved Therapy

Study describes the structural and functional effects of several mutations on the androgen receptor

New details on how immune cells 'see' and respond to mutations in cancer cells may lead to more targeted and effective immunotherapy