Mutations

In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication (translesion synthesis).

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How a small number of mutations can fuel outbreaks of western equine encephalitis virus

Mass General Brigham researchers identify mutations that can lead to resistance to some chemotherapies - EurekAlert

Researchers identify mutations that can lead to resistance to some chemotherapies

Mutations disrupt touch-based learning, study finds - EurekAlert

New technique reveals how the same mutations give rise to very different types of leukaemia

New technique reveals how the same mutations give rise to very different types of leukaemia - EurekAlert

'Perfect storm' of mutations drives infection-triggered autoimmune disease

DNA damage can last unrepaired for years, changing our view of mutations

Bird Flu Samples From Very Ill Patient Had ‘Concerning’ Mutations

Understanding how mutations affect diseases

Understanding how mutations affect diseases - EurekAlert

New study unveils the impact of mutations in the calcium release channel on muscle diseases - EurekAlert

‘Silent’ mutations found to have repercussions beyond their own gene - EurekAlert

'Silent' mutations found to have repercussions beyond their own gene

Mutations in DNA damage repair genes associat - EurekAlert

Mutations of the spike gene do not predict the severity of variants of SARS-CoV-2 - EurekAlert

Mutations in wheat TaAPA2 gene result in pleiotropic effects on plant architecture - EurekAlert

Mutations in noncoding DNA become functional in some cancer-driving genes

Our thirst for pineapple may be causing mutations in Costa Rica’s sloths