Gene Network

A gene regulatory network is a collection of molecular regulators that interact with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins which, in turn, determine the function of the cell. GRN also play a central role in morphogenesis, the creation of body structures, which in turn is central to evolutionary developmental biology. The regulator can be DNA, RNA, protein and complexes of these. The interaction can be direct or indirect. In general, each mRNA molecule goes on to make a specific protein. In some cases this protein will be structural, and will accumulate at the cell membrane or within the cell to give it particular structural properties. In other cases the protein will be an enzyme, i.e., a micro-machine that catalyses a certain reaction, such as the breakdown of a food source or toxin.

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Butterfly Eyespots Reuse Gene Network That Patterns Antennae, Legs and Wings

Gene Network changes associated with cancer onset and progression identify new candidates for targeted gene therapy