Latest research suggests 10 treatments help treatment-resistant depression: extending the original antidepressant trial, switching antidepressants, combining antidepressants, IV ketamine, intranasal ketamine, second-gen antipsychotics, ECT, rTMS, vagus nerve stimulation, and psychotherapy.

New study supports medical safety of electroconvulsive therapy (ECT)

Pandemic shows essential role of ECT as treatment for severe depression