Crohn

Crohn's disease is a type of inflammatory bowel disease that may affect any segment of the gastrointestinal tract from the mouth to the anus. Symptoms often include abdominal pain, diarrhea, fever, abdominal distension, and weight loss. Other complications outside the gastrointestinal tract may include anemia, skin rashes, arthritis, inflammation of the eye, and fatigue. The skin rashes may be due to infections as well as pyoderma gangrenosum or erythema nodosum. Bowel obstruction may occur as a complication of chronic inflammation, and those with the disease are at greater risk of colon cancer and small bowel cancer. While the precise causes of Crohn's disease are unknown, it is believed to be caused by a combination of environmental, immune, and bacterial factors in genetically susceptible individuals. It results in a chronic inflammatory disorder, in which the body's immune system defends the gastrointestinal tract, possibly targeting microbial antigens.

Read more in the app

Apply single-cell analysis to reveal mechanisms of a common complication of Crohn's disease

Implantable sensor could lead to timelier Crohn's treatment

79% of Crohn's disease patients in remission after early intervention

Treating newly-diagnosed Crohn's patients with advanced therapy leads to dramatic improvements in outcomes

Early drug treatment leads to better outcomes for Crohn’s disease

Mood interventions may reduce inflammation in Crohn's and Colitis

Comprehensive guideline on using biomarkers for monitoring Crohn's disease

Blood Tests Can Reveal Crohn's Disease 8 Years Before Diagnosis

New Vaccine Can Completely Reverse Autoimmune Diseases Like Multiple Sclerosis, Type 1 Diabetes, and Crohn’s Disease

Neonatal stem cells from the heart could treat Crohn's disease

Crohn's Disease: Scientists Say Bacteria in The Mouth May Be a Cause

Nanofiber-Hydrogel Shows Success Treating Severe Complication of Crohn’s Disease

Research finds hope in stem cell therapy for perianal fistulas in patients with Crohn's disease

Nanofiber-hydrogel loaded with stem cells shows success treating severe complication of Crohn's disease

To trigger Crohn's disease, pathogenic bacteria co-opt a genetic susceptibility

Nanoparticle Probiotic “Backpacks” Show Promise for Treating Inflammatory Bowel Diseases Like Crohn’s and Ulcerative Colitis

Crohn’s Mystery Solved? Common Stomach Bug May Help Cause Inflammatory Bowel Disease

Norovirus link to Crohn's disease may point to new therapies

Crohn's disease diet: What to eat and what to avoid to manage symptoms

Study zeroes in on genes involved in Crohn's disease