SpaceX Crew-5 will be the fifth crewed operational NASA Commercial Crew flight of a Crew Dragon spacecraft, and the eight overall crewed orbital flight. The mission is planned for launch in September 2022. The Crew-5 mission will transport four crew members to the International Space Station. As of December 2021, two NASA astronauts, one JAXA astronaut and one Russian cosmonaut have been assigned to the mission. Three of the currently assigned crew members were assigned following delays to Boeing's Starliner. Commander Nicole Mann was reassigned to the flight from Boeing's Boe-CFT mission, while Pilot Josh Cassada and Mission Specialist Koichi Wakata transferred from Boeing Starliner-1. Anna Kikina was reassigned from Soyuz MS-22. Three of the four crew members are making their first space flight.

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