Reinvigorating exhausted T cells in cancer and chronic viral infections cells. However, in chronic viral infection and cancer, the killer cells often lapse into “exhausted” CD8+ T cells that no longer can stem disease - EurekAlert!
Researchers reveal how aging impairs antitumor activity of CD8+ T cells - EurekAlert
'Cutting the cable' between CD8+ T and T regulatory cells enhances checkpoint immunotherapy