CALLISTO is a single stage and reusable VTVL demonstrator propelled by rocket engine and developed jointly by the German Aerospace Center, the French Space Agency, and the Japanese Aerospace Exploration Agency. The goals are to mature and demonstrate the technologies which are necessary to build and operate a reusable launch vehicle, but also to better assess the operational cost of such a vehicle. The first flight is planned for 2022. Eventually, lessons learned with the development of CALLISTO will pave the way to develop the European reusable launcher Ariane Next.

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ESA's mission to Jupiter's icy moons ready for launch | It will conduct 35 fly-bys of Callisto, Ganymede and Europa before permanently settling into an orbit around Ganymede. It has an advanced package of instruments to investigate whether any of these moons are habitable.