Aduhelm
Aducanumab, sold under the brand name Aduhelm, is a medication designed to treat Alzheimer's disease. It is an amyloid beta-directed monoclonal antibody that targets aggregated forms of amyloid beta found in the brains of people with Alzheimer's disease to reduce its buildup. Aducanumab was approved for medical use in the United States by the Food and Drug Administration in June 2021, in a controversial decision that led to the resignation of three advisers to the FDA in the absence of evidence that the drug is effective. The FDA stated that it represents a first-of-its-kind treatment approved for Alzheimer's disease and that it is the first new treatment approved for Alzheimer's since 2003. Aducanumab's approval is controversial due to ambiguous clinical trial results surrounding its efficacy.
