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Brain circuits underlying learning from negative experiences - EurekAlert


A new research from the Laboratory of Systems Neuroscience of the Institute of Experimental Medicine, Budapest, Hungary suggests that long-range inhibitory parvalbumin-expressing basal forebrain neurons are recruited by aversive stimuli to serve crucial associative learning functions through increasing cortical excitability at specific target areas, probably by disinhibition. Thus, at least for aversive stimuli, parvalbumin-expressing basal forebrain neurons might be the physical substrate of the ‘attention for learning’ concept.

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