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Audit Published in Research Integrity and Peer Review Identifies Key Failings of Institutional Animal Care and Use Committees: Scientists compile first substantive update to IACUC guidelines since 1963

WASHINGTON, D.C.— A focused review published in the journal Research Integrity and Peer Review has found that Institutional Animal Care and Use Committees (IACUC) provide surprisingly little protection for animals in research, that searches for alternatives to animal use are seldom conducted, and that, when performed, they are inadequate. For the first time since the publication of “The Guide for the Care and Use of Laboratory Animals” (The Guide) in 1963, research scientists are recommending a new guide that puts replacement of animals in research and IACUC member training at the forefront.

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