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An epigenome editing toolkit to dissect the mechanisms of gene regulation - EurekAlert
<p>A study from the Hackett group at EMBL Rome led to the development of a powerful epigenetic editing technology. The system unlocks the ability to precisely program chromatin modifications at any specific position in the genome, to understand their causal role in transcription regulation. This innovative approach will help to investigate the role of chromatin modifications in many biological processes, and to program desired gene activity responses, which may prove useful in disease settings.</p>
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