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Advancement in modulation of brain extracellular space and unlocking its potential for intervention of neurological ... - EurekAlert


Cells in the brain are surrounded by extracellular space (ECS), which forms porous nets and interconnected routes for molecule transportation. Emerging evidence supports that dysregulation of brain ECS contributes to the pathogenesis and development of many neurological disorders, highlighting the importance of therapeutic modulation of brain ECS function. This review emphasizes modulation methods to manipulate ECS with implications to restore their function in brain diseases.

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