Get the latest Science News and Discoveries

Active plant substance reduces pulmonary hypertension - EurekAlert


Pulmonary hypertension is a very serious disease that leads to heart failure and death in many patients. Searching for new treatment options, a team headed by Professor Daniela Wenzel and Dr. Alexander Seidinger from the Department of Systems Physiology at Ruhr University Bochum, Germany, tested the plant substance FR900359 – referred to as FR by the researchers. It differs from previously used active substances in that it targets a different point in the signaling pathway that leads to pulmonary hypertension. As a result, it simultaneously inhibits numerous factors that lead to vasoconstriction in the lungs. “In our experiments, FR relaxed the vessels quickly and effectively and produced a good therapeutic effect,” as Alexander Seidinger, first author of the study, outlines the findings. The results were published in the journal EMBO Molecular Medicine on July 8, 2024.

None

Get the Android app

Or read this on Eureka Alert

Read more on:

Photo of EurekAlert

EurekAlert

Related news:

News photo

Dante on the Move: Refugee’s share experiences through the lens of 14th century poet - EurekAlert

News photo

Argonne develops new kind of AI model for weather prediction - EurekAlert

News photo

Study: Nanoparticle vaccines enhance cross-protection against influenza viruses - EurekAlert