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A study led by UPF describes how insulinomas, a rare type of pancreatic beta cell tumor, form - EurekAlert
The cause is a change in the epigenetic pattern of the beta cells of the pancreas, which overexpress oncogenes and genes related to insulin production, thus altering their functioning. This change in pattern, a common factor in the vast majority of tumours, is due to the accumulation of different mutations in genes involved in the regulation of gene expression.
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