Get the latest Science News and Discoveries
A promising target for new RNA therapeutics now accessible - EurekAlert
<p><strong>Only recently, a new era in medicine began with the first RNA vaccines. These active substances are modified RNAs that trigger immune responses of the human immune system. Another approach in RNA medicine targets the body's own RNA and its protein modulators by specifically tailored active substances. Scientists around Peng Wu, research group leader at the Chemical Genomics Centre at the Max Planck Institute of Molecular Physiology in Dortmund, have now developed the first small-molecule inhibitors against the RNA-modifying enzyme METTL16. The methyltransferase is responsible for the regulation of different RNAs and is a promising anti-cancer target. The new findings lay the foundation for a comprehensive investigation of the role of METTL16 in health and disease and are a step closer towards the development of therapeutic agents targeting such RNA modifiers.</strong></p>
None
Or read this on Eureka Alert