Get the latest Science News and Discoveries
100% of ME/CFS (chronic fatigue syndrome) patients have Genetic Mutation of IDO2. This forces reliance on IDO1 to produce kynurenine from tryptophan. If tryptophan levels in a cell rise too high, then IDO1 will stop making kynurenine & tryptophan levels will remain high. IDO metabolic trap.
None
Or read this on r/EverythingScience