Get the latest Science News and Discoveries

Mitochondrial fission factor senses and governs ferroptosis


The mitochondrial–peroxisomal fission adaptor MFF is identified as a selective pro-ferroptotic mediator, and the newly developed MFF–SPARK sensor enables high-content screening of ferroptosis-sensitizing compounds and the discovery of upstream regulators of MFF.

None

Get the Android app

Or read this on Nature

Read more on:

Photo of ferroptosis

ferroptosis

Photo of governs

governs

Related news:

News photo

Gramine suppresses triple-negative breast cancer by inducing ferroptosis via CUL3-mediated ubiquitination of MTDH - EurekAlert!

News photo

A molecular switch in ferroptosis - EurekAlert!

News photo

ATP depletion the key driver of ferroptosis in Alzheimer’s brains