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Lsp2 links mTORC1 to TOP mRNA translation and lifespan in <i>Drosophila</i>


In Drosophila, the protein Lsp2, which is induced by dietary essential amino acids, is a key physiological effector of mTORC1, and mutant flies that lack the Lsp2 gene exhibit reduced translation of TOP mRNAs and improved longevity.

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mTORC1

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Drosophila</i

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