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Ancient DNA solves 12,000-year-old mystery of rare genetic growth disorder


An Ice Age double burial in Italy has yielded a stunning genetic revelation. DNA from a mother and daughter who lived over 12,000 years ago shows that the younger had a rare inherited growth disorder, confirmed through mutations in a key bone-growth gene. Her mother carried a milder version of the same mutation. The finding not only solves a long-standing mystery but also proves that rare genetic diseases stretch far back into prehistory.

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