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A donut-shaped protein breaks apart to start bacterial cell division

Researchers have revealed how bacteria precisely control the genes that trigger cell division. The study shows that the MraZ protein, which normally forms a donut-shaped structure, must bend and partially break apart to bind key DNA sequences that activate division genes. Using cryo-electron microscopy, scientists captured this interaction in remarkable detail. The mechanism appears to be widespread across bacteria, offering a new window into how microbes regulate growth.

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